Representing 3–5% of the microbial community, Akkermansia muciniphila is commonly found in the human gut. Rigorously studied in recent years, A. muciniphilia has been inversely associated with cardiovascular disease, obesity, diabetes, inflammation, and liver disease.

A. muciniphila is a game-changer in the realm of probiotics, and a cornerstone to AKKA's advanced formula. In its most potent form — preserved pasteurized — it has the ability to support liver function while enhancing the intestinal barrier and boosting metabolic health.

Quercetin is a naturally occurring flavonoid, which helps neutralize harmful free radicals in the body. Further known for its anti-inflammatory and antioxidant properties, Quercetin is also a powerful liver protectant and Akkernamsia amplifier, making it highly beneficial for health in multiple ways.  

Multiple studies have demonstrated that quercetin prevents both fatty liver and damage from alcohol, in addition to reducing scarring of the liver.

A potent polyphenolic compound, Resveratrol plays a key role in metabolic detoxification and health maintenance. It not only prevents the formation of new fat cells but also enhances fat burning through a process known as thermogenesis. 

By boosting bile production, resveratrol further improves digestion and aids in the efficient removal of toxins, optimizing liver function. Additionally, it strengthens the intestinal barrier, preventing unwanted substances from entering the bloodstream and safeguarding overall liver health.

Silymarin is currently the world's most effective treatment for liver disease. It has shown positive effects in treating nearly every known form of liver disease including cirrhosis, hepatitis, and necrosis, and liver damage from substance abuse.

Silymarin may enhance three availableth factors (HGF, TGFα, and TGFβ1), acting as a cell cycle progression agent that triggers liver regeneration to protect the liver as a hepatoprotective agent for liver disease. 

Artichoke leaf extract has a long history of being used in traditional medicine as a treatment for digestive and liver issues. Full of protective and regenerative properties, artichoke leaf extract not only improves blood flow, but also reduces overall cholesterol and triglycerides. 

Emerging evidence further suggests that artichoke leaf extract’s beneficial properties include helping to lower blood pressure, reduce inflammation in the liver, and facilitate weight loss.